tag:blogger.com,1999:blog-3734925856292601239.post1864462747620305543..comments2024-03-22T15:55:34.030-04:00Comments on Evo and Proud: African Americans and vitamin DPeter Frosthttp://www.blogger.com/profile/04303172060029254340noreply@blogger.comBlogger19125tag:blogger.com,1999:blog-3734925856292601239.post-69767589019650261592016-08-13T04:47:41.525-04:002016-08-13T04:47:41.525-04:00How can he life without sunlight, he started up ag...How can he life without sunlight, he started up again faster and Keep in mind, that Michael Jackson had a life threatening disease, possible that his lungs stop working. Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3734925856292601239.post-56860846551196292122015-10-02T04:13:03.049-04:002015-10-02T04:13:03.049-04:00Unfortunately, there are millions of people out th...Unfortunately, there are millions of people out there who are now taking mega-doses of vitamin D every day. The mass experiment has already begun and the results should be ready in a decade or so, particularly among African Americans.idealshttps://www.idealsvdr.com/noreply@blogger.comtag:blogger.com,1999:blog-3734925856292601239.post-56838125639222875512014-04-12T04:07:08.897-04:002014-04-12T04:07:08.897-04:00If you're interested in reading about a Pigmen...If you're interested in reading about a Pigmentation Treatment,than click <a href="http://skindelhi.com/pigmentation.html" rel="nofollow">Pigmentation Treatments Delhi</a>,http://skindelhi.com/pigmentation.html<br />Allanhttps://www.blogger.com/profile/04414023777592108747noreply@blogger.comtag:blogger.com,1999:blog-3734925856292601239.post-26290379477577598562010-01-08T08:56:08.533-05:002010-01-08T08:56:08.533-05:00You're wrong, and as expected are trying to cl...You're wrong, and as expected are trying to claim any study showing no benefit from anti-oxidants was badly designed. But you show me a single study of anti-oxidants with positive results - there aren't any. And by the way Vit E is not the worst of them for example beta carotene supplements are proven to cause more than 'a bit' of excess mortality in fact a study was stopped because of the excess mortality.<br /><br />If anti-oxidants are bad then pro-oxidants should be good, lo and behold <a href="http://leherensuge.blogspot.com/2009/10/uk-brown-gets-rid-of-honest-drug.html?showComment=1257664762475#c578797856743413501" rel="nofollow">alcohol is</a>. Here is the <a href="http://leherensuge.blogspot.com/2009/10/uk-brown-gets-rid-of-honest-drug.html?showComment=1257848974740#c1427508142138279261" rel="nofollow">explaination why</a>.<br /><br />The evidence is inexorably mounting up against anti-oxidants, the vitamin D story is going to go the same way. <br /><br /><a href="http://evoandproud.blogspot.com/2010/01/predictions-for-2010.html" rel="nofollow">Population differences in vitamin D metabolism</a>.<br /><br /><a href="http://www.nmanet.org/images/uploads/Publications/LTE1309.pdf" rel="nofollow">Black-White Differences<br />in Cancer Risk and the<br />Vitamin D Hypothesis</a>Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3734925856292601239.post-64785348313804159202009-12-28T13:34:01.603-05:002009-12-28T13:34:01.603-05:00Hi,
I am The assistant editor with disease.c...Hi,<br /> I am The assistant editor with disease.com. I really liked your site and I am interested in building a relationship with your site. We want to spread public awareness. I hope you can help me out. Your site is a very useful resource.<br /><br />Please email me back with your URl in subject line to take a step ahead an to avoid spam.<br /><br />Thank you,<br />Lisa Hope<br />lisa.disease.com@gmail.comUnknownhttps://www.blogger.com/profile/02298045014531485925noreply@blogger.comtag:blogger.com,1999:blog-3734925856292601239.post-34275480972462338862009-12-03T04:26:58.193-05:002009-12-03T04:26:58.193-05:00Vit D supplementation (with calcium) already has s...Vit D supplementation (with calcium) already has slashed all-cancer rate 60-77% in RCT (Lappe et al 2007) and medical literature has lots of data to prove that raising Vit D levels by supplementation has good effects on infections, HDL cholesterol, blood pressure, pain and so on.<br /><br />As for antioxidant supplementation, Vit E as d-alphatocoferol did raise a bit mortality and it may have been because d-alfa consumes gammatocoferol, another Vit E form.Neonomidehttps://www.blogger.com/profile/00961709424324961929noreply@blogger.comtag:blogger.com,1999:blog-3734925856292601239.post-56780949021470090372009-11-08T12:59:08.511-05:002009-11-08T12:59:08.511-05:00Re studies like Annamari Kilkkinen's as a rat...Re studies like Annamari Kilkkinen's as a rationale for <i>ingesting</i> enough D to raise serum 25(OH)D levels <br /><br />Low levels of antioxidants were found in ill people, but when they ran trials where people took combinations of antioxidants in pills the raising of blood levels produced no benefit. More than one of the trials had to be stopped due to excess mortality. The rationale for taking vitamin D pills is the same as was given for antioxidants and will produce the same results.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3734925856292601239.post-12746340200377179022009-11-08T03:12:32.674-05:002009-11-08T03:12:32.674-05:00Maybe researchers should use another rodent for dr...Maybe researchers should use another rodent for drawing conclusions about vitamin D and aging<br /> 'Prolonged longevity in naked mole-rats: age-related changes in metabolism, body composition and gastrointestinal function' <br /><br />Quote:<br />Maximum lifespan of these 40 g rodents (>27 year) is 9 times greater than predicted allometrically. [...]The observed absence of age-related bone loss in naked mole-rats may be explained by their employment of vitamin D-independent mineral metabolism.<br /><br /><a href="http://www.springerlink.com/content/w065v848587280q6/" rel="nofollow">Slow Aging: Insights from an Exceptionally Long-Lived Rodent, the Naked Mole-Rat</a><br /><br /><a href="http://biomed.gerontologyjournals.org/cgi/content/full/60/11/1369" rel="nofollow">The Naked Mole-Rat: A New Long-Living Model for Human Aging Research </a>.<br />"Indeed, to date we have not found a single incidence of cancer in more than 250 necropsies of NMRs undertaken in animals ranging from 2 to 25 years and have not noticed any tumors in living animals (our unpublished observations based on animals at CCNY and three zoos). This is all the more surprising, as vitamin D metabolites have been implicated as potent anti-mitogenic agents, and NMRs are naturally deficient in this prohormone"Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3734925856292601239.post-80560818897031649812009-11-05T14:26:05.765-05:002009-11-05T14:26:05.765-05:00Neonomide ,
Reinhold Vieth's enzyme depletion ...Neonomide ,<br />Reinhold Vieth's enzyme depletion theory is linked to in comments on an earlier post. There are several posts here about vitamin D which you may find informative.<br /><br />Re. the conclusions of Tuohimaa based on mice, don't give him all the credit. Here's a Harvard study from 2006<br /><br /><a href="http://www.ncbi.nlm.nih.gov/pubmed/16731043" rel="nofollow">Hypervitaminosis D and premature aging: lessons learned from Fgf23 and Klotho mutant mice.</a><br />" Such in vivo experimental studies indicated that excessive vitamin-D activity and altered mineral-ion homeostasis could accelerate the aging process".<br /><br /><br /><a href="http://cmbi.bjmu.edu.cn/news/report/2004/DIA/13.pdf" rel="nofollow">Infant Vitamin D Supplementation and<br />Allergic Conditions in Adulthood<br />Northern Finland Birth Cohort 1966</a>.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3734925856292601239.post-34850605119532817332009-10-19T18:12:14.003-04:002009-10-19T18:12:14.003-04:00Hypercalcemia is only observed when you use Vitami...Hypercalcemia is only observed when you use Vitamin D2. Vitamin D3 does not cause hypercalcemia. If you have any doubts you can read "Am J Clin Nutr. 2008 Jun;87(6):1952-8.<br />Vitamin D intake to attain a desired serum 25-hydroxyvitamin D concentration.<br />Aloia JF, Patel M, Dimaano R, Li-Ng M, Talwar SA, Mikhail M, Pollack S, Yeh JK.<br />Bone Mineral Research Center, Winthrop University Hospital, Mineola, NY, USA." or "J Bone Miner Res. 2007 Dec;22 Suppl 2:V64-8.<br />Vitamin D toxicity, policy, and science.<br />Vieth R.<br />Departments of Nutritional Sciences, and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada."Pascalhttps://www.blogger.com/profile/10789644705470077386noreply@blogger.comtag:blogger.com,1999:blog-3734925856292601239.post-1257320040358586432009-10-13T12:52:43.595-04:002009-10-13T12:52:43.595-04:00Hello from Finland and congrats for some interesti...Hello from Finland and congrats for some interesting observations there on Vitamin D!<br /><br />A few points:<br /><br />Tuohimaa - a finnish researcher by the way - is notorious for making vague extrapolations on the basis of his OWN cancer studies, some his OWN limited mice work and seems to refuse other explanations for U-shaped cancer risks in (only) HIS studies, like Reinhold Vieth's enzyme depletion theory here:<br /><br />http://www.ncbi.nlm.nih.gov/pubmed/19667164<br /><br /><br />Also please check these 25(OH)D results for nigerian toddlers (who typically are in diapers, while adults dress a lot):<br /><br />http://wildhorse.insinc.com/directms13oct2005/Slides.htm_28slide.jpg<br /><br /><br />Also note that grains and especially wheat is known to deplete vitamin D levels, so this *might* explain those results for people in India.<br /><br />Hawaiian study simply was not good - people were in the sun less than they reported.Neonomidehttps://www.blogger.com/profile/00961709424324961929noreply@blogger.comtag:blogger.com,1999:blog-3734925856292601239.post-4453759005319035242009-10-08T14:46:00.281-04:002009-10-08T14:46:00.281-04:00er heard that about Vitamin D. My doctor recommend...er heard that about Vitamin D. My doctor recommended a very high dosage for me. Maybe I should tone it down!Geophilehttps://www.blogger.com/profile/17206319191769614929noreply@blogger.comtag:blogger.com,1999:blog-3734925856292601239.post-36213510825650714482009-09-04T17:57:28.588-04:002009-09-04T17:57:28.588-04:00"Your conclusions about MJ are completely cra..."Your conclusions about MJ are completely crap, and so is your whole theory about aging and vitamin D."<br /><br />Thanks for the kind words. Two points:<br /><br />1. African Americans normally have low vitamin D levels. So it's hardly surprising that Michael Jackson's levels were 'a bit low' before any 'nutritional treatment'. Also keep in mind that the recommended daily intake has been progressively raised.<br /><br />2. Did the nutritional treatment include vitamin D megadoses? MJ's nurse doesn't address this question. I suspect that she diagnosed vitamin D insufficiency and acted accordingly.Peter Frostnoreply@blogger.comtag:blogger.com,1999:blog-3734925856292601239.post-1585905229432235432009-09-04T17:51:05.797-04:002009-09-04T17:51:05.797-04:00A low 25D lab result does not rule out supplementa...A low 25D lab result does not rule out supplementation. A high 1,25D (which is not routinely tested) can create an enzymatic feedback signal to lower the conversion to 25D.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3734925856292601239.post-70174027639262170382009-07-29T17:34:04.302-04:002009-07-29T17:34:04.302-04:00Michael Jackson's nurse Cherilyn Lee said: &qu...Michael Jackson's nurse Cherilyn Lee said: "his vitamin D level was a little low" in:<br /><br />“Before any nutritional treatment I do comprehensive lab work. I did a complete blood panel and there were no red flags,” she said. “Because of his diet his blood sugar was a little low, but not to the point it would cause a problem; his vitamin D level was a little low. Folic acid — and that includes an anemia panel — fine. Every organ system was checked out. There were no indicators of heart disease. The C-reactive protein test? Nothing there (The test is a general marker of inflammation throughout the body, and can rule out things like coronary heart disease and cardiovascular disease). His hemoglobin A1c, which would have indicated diabetes, fine. His liver functions, kidney functions, they were all fine. He was healthy.”<br /><br />Your conclusions about MJ are completely crap, and so is your whole theory about aging and vitamin D.ferdonoreply@blogger.comtag:blogger.com,1999:blog-3734925856292601239.post-26680011652978097092009-07-11T11:28:13.167-04:002009-07-11T11:28:13.167-04:00RG,
They aren't his. The rumor mill has it th...RG,<br /><br />They aren't his. The rumor mill has it that the sperm came from his dermatologist.<br /><br />Anon, Tod,<br /><br />Yes, it's just a supposition, but it's one that makes sense to me for two reasons:<br /><br />a) MJ was a vitamin maniac;<br /><br />b) He was continually surrounded by doctors and quack doctors. Some of them would have surely told him to take vitamin D once he began limiting sun exposure.<br /><br />Maybe this post will spur someone to find out whether he was taking mega-doses of vitamin D.Peter Frostnoreply@blogger.comtag:blogger.com,1999:blog-3734925856292601239.post-43128770305929352702009-07-11T06:49:00.448-04:002009-07-11T06:49:00.448-04:00It's virtually certain that someone avoiding s...It's virtually certain that someone avoiding sunlight for decades was taking the 'sunshine vitamin'. The dosage was probably increased in the last years in line with the current enthusiasm for boosting African Americans' levels.<br /> <br /><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=19500727" rel="nofollow">Premature aging in vitamin D receptor mutant mice.</a>.<br /> There was no difference either in the structure of cerebellum or in the number of Purkinje cells. Unlike the wildtype controls, VDR KO mice lose their ability to swim after 6 months of age. Expression of all the genes was lower in old VDR KO mice, but only NF-kappaB, Fgf-23, p53 and IGF1R were significantly lower. Since the phenotype of aged VDR knockout mice is similar to mouse models with hypervitaminosis D(3), our study suggests that VDR genetic ablation promotes premature aging in mice, and that vitamin D(3) homeostasis regulates physiological aging.<br /><br /><br />1) J Steroid Biochem Mol Biol. 2009 Jul;115(3-5):91-7Todnoreply@blogger.comtag:blogger.com,1999:blog-3734925856292601239.post-69807368251014777282009-07-10T22:11:27.436-04:002009-07-10T22:11:27.436-04:00Hmmm, given all the mega-bad aspects to MJ's l...Hmmm, given all the mega-bad aspects to MJ's lifestyle, why bother to suggest Vitamin D, when it's all supposition that he was even ingesting Vitamin D.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3734925856292601239.post-32041525956300604982009-07-10T09:28:35.134-04:002009-07-10T09:28:35.134-04:00Did he bleached his kids too?, how can they be so ...Did he bleached his kids too?, how can they be so white if they are really his?RGnoreply@blogger.com